"They demonstrated this season - winning against City and PSG - that we will have to be very attentive and not think that the game will be easy".
While a goalless draw away from home isn't the worst result in the world and Barcelona will be confident they can progress at Camp Nou, a draw could suit Lyon. The match was played in the Camp Nou in Barcelona.
Lyon captain Nabil Fekir is banned and key midfielder Tanguy Ndombele is a doubt.
"Sometimes you can not be brilliant in every game, but I think the team is ready to play at its very best", he said.
Lyon and Barcelona's last competitive encounter came 10 years ago, in the round of 16 of the 2008/09 Champions League. The World Cup victor scored the goal that gave them a 1-1 draw at Shakhtar Donetsk in their last group game to take them through, but a booking a few minutes later means he is suspended here.
Coach Ernesto Valverde has played down the significance of his side's recent slack displays.
They may have finished the group stage unbeaten but they only won one match and conceded 11 goals in just six games.
That said, on Saturday in a narrow 1-0 win over Real Valladolid, Suarez came on as a substitute for the last half-hour and spurned four clear chances created for him by Messi.
The humiliation against Roma was mainly caused by a pragmatic approach from Valverde that allowed Roma to control proceedings and maintain pressure on the Barcelona back line.
The La Liga giants looked set for a semi-final berth after winning the first leg 4-1 at home but capitulated in the Italian capital, going out on away goals after a humiliating 3-0 defeat.
Ultimately the Germans will head into the second leg the happier of the two, even if it was an off-night away from home in the Champions League knockout stages for their star front man Lewandowski. What I don't like is if we don't have any chances. The Blaugrana will hope to win a knockout game on the road for the first time since 2016, ending a five-game victory drought.