Australia reduced Pakistan to 45-3 by stumps, with nightwatchman Bilal falling to Lyon for a duck and Jon Holland accounting for first-innings centurion Mohammad Hafeez (17) as well as Azhar Ali (4).
Pakistan began day two at 255/3 with Haris Sohail and Mohammad Abbas on the crease.
Preview: It was yet another attritional, old-fashioned day of cricket at the Dubai International Cricket Stadium and by the end of it Haris Sohail's maiden Test ton ensured Pakistan held the aces when stumps were drawn on Day 2 of the first Test between Australia and Pakistan on Monday.
All seemed to be well for the Australians at lunch with openers Aaron Finch and Usman Khawaja batting solidly against Pakistan's spinners to take their team to 137 without loss at lunch.
But Australia did well in the last 29 overs of the day with seamers getting the reverse swing and the spinners also finding some turn off the wicket.
Travis Head, Aaron Finch and Marnus Labuschagne are making their debut for Australia.
Before Asif´s brilliance Abbas had forced Finch to drive straight into the hands of Asad Shafiq at short mid-on.
Khawaja hit eight fours before miscuing a premeditated sweep and was caught at short leg while Finch had five boundaries and a six in his knock.
Asif has figures of 4-28 in 17 overs.
Earlier in the day Finch was more confident as he punched two boundaries and a six off Yasir before sweeping Asif for a boundary to reach his half-century.
"I didn't play test cricket for over two years, but I always backed myself", Hafeez said, after hitting 15 fours in his 208-ball 10th test hundred that spanned almost 4 1/2 hours. There were the odd LBW shouts and the occasional play and miss, but both Sohail and Shafiq looked largely settled on a track which had very little to offer to the bowlers.