The latest 007 film, which is yet to have been titled, is now in production and was expected to be released in November 2019.
The news comes almost three months to the day since Boyle was confirmed to direct the film, following months of speculation.
Sources tell Variety Eon and Boyle were in the early stages of casting the new Bond girl and villain prior to the December production start.
The pair previously worked together on a short film for the London 2012 Olympics.
Daniel Craig will play the central role in the as-yet-untitled 25th Bond film.
The next James Bond movie has lost its director.
Creative differences is the most milquetoast excuse Hollywood has for anything so we really don't know what the hell is going on, but I'm honestly a bit surprised about this.
The internet has been buzzing for months - if not years - about the possibility of British actor Idris Elba taking over.
It was also viewed as a surprise that the filmmaker, who had avoided franchises in the past, would board the Bond machine.